Polyethyleneimine-modified calcium carbonate nanoparticles forp53gene delivery
نویسندگان
چکیده
منابع مشابه
Polyethyleneimine-modified calcium carbonate nanoparticles for p53 gene delivery
In this study, calcium carbonate (CaCO3) nanoparticles with spherical structure were regulated by arginine and successfully synthesized via a facile co-precipitation method. The average particle size of as-prepared CaCO3 was about 900 nm. The properties of nanostructured CaCO3 particles were characterized by scanning electron microscope, Fourier transform infrared spectroscopy, X-ray diffractio...
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To improve the performance of nanostructured calcium carbonate in gene delivery, a hydrophilic polysaccharide, alginate, was added to calcium carbonate co-precipitation systems to form alginate/CaCO(3)/DNA nanoparticles. The size and ζ-potential of the nanoparticles were measured by a zetasizer. Due to the existence of alginate chains which retarded the growth of calcium carbonate based co-prec...
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ژورنال
عنوان ژورنال: Regenerative Biomaterials
سال: 2016
ISSN: 2056-3418,2056-3426
DOI: 10.1093/rb/rbv029